When a Nontuberculous Mycobacterial Infection Reveals an Error of Immunity: A Single Center's Experience

Alessia Morreale; Laura Dotta; Donatella Vairo; Tullia Bazzana; Vassilios Lougaris; Annarosa Soresina; Alessandro Plebani; Silvia Clara Giliani; Fulvio Porta; Alberto Matteelli; Luca Oscar Redaelli De Zinis; Raffaele Badolato

doi:10.1097/INF.0000000000003461

When a Nontuberculous Mycobacterial Infection Reveals an Error of Immunity: A Single Center's Experience

Pediatr Infect Dis J. 2022 May 1;41(5):427-429. doi: 10.1097/INF.0000000000003461.

Affiliations

¹ From the Department of Pediatrics, ASST Spedali Civili of Brescia, University of Brescia.
² Department of Pediatrics, Institute for Molecular Medicine A. Nocivelli, ASST Spedali Civili of Brescia.
³ Department of Molecular and Translational Medicine, Institute for Molecular Medicine A. Nocivelli, University of Brescia.
⁴ Department of Pediatric Otorhinolaryngology, ASST Spedali Civili of Brescia.
⁵ Department of Pediatrics, Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST Spedali Civili of Brescia.
⁶ Department of Pediatrics, ASST Spedali Civili of Brescia.
⁷ Institute for Molecular Medicine A. Nocivelli, Department of Pathology, Laboratory of Genetic Disorders of Childhood, Department of Molecular and Translational Medicine, University of Brescia, ASST Spedali Civili of Brescia.
⁸ Department of Pediatric Onco-Hematology and BMT, ASST Spedali Civili of Brescia.
⁹ Department of Infectious and Tropical Diseases, WHO Collaborating Centre for TB/human immunodeficiency virus and TB Elimination, University of Brescia and ASST Spedali Civili of Brescia.
¹⁰ Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, Section of Head and Neck Surgery, University of Brescia, Pediatric Otorhinolaryngology Head Neck Surgery Division, Children Hospital, ASST Spedali Civili of Brescia, Brescia, Italy.

PMID: 35086117
DOI: 10.1097/INF.0000000000003461

Abstract

We present an algorithm that may be applied in case of a diagnosis of pediatric nontuberculous mycobacterial disease to identify the patients who may require an immunologic assessment to discover a possible underlying immune system defect predisposing to their nontuberculous mycobacterial infections.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child
Humans
Mycobacterium Infections, Nontuberculous* / diagnosis
Mycobacterium Infections, Nontuberculous* / microbiology
Nontuberculous Mycobacteria