Technical procedures and REDCap tools for internet-based clinical trials

Ananta S Bangdiwala; David R Boulware

doi:10.1016/j.cct.2021.106660

Technical procedures and REDCap tools for internet-based clinical trials

Contemp Clin Trials. 2022 Mar:114:106660. doi: 10.1016/j.cct.2021.106660. Epub 2022 Jan 25.

Authors

Ananta S Bangdiwala¹, David R Boulware²

Affiliations

¹ School of Public Health, University of Minnesota, Minneapolis, MN, USA. Electronic address: Ananta@umn.edu.
² Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Abstract

In March of 2020 our team of researchers developed and opened three clinical trials to investigate hydroxychloroquine as prophylaxis or treatment for the coronavirus disease 2019 (COVID-19). We simultaneously built corresponding Research Electronic Data Capture (REDCap) projects for these low-touch, remote trials that relied on participant-reported data. REDCap has built-in features that support pragmatic, internet-based studies, and REDCap is flexible enough to allow creative solutions for specific trials. We describe challenges, choices, and suggestions based on our experience with REDCap for our COVID-19 trials.

Keywords: Automation; Clinical trials; Covid-19; Data base management; Patient-oriented research; Survey.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

COVID-19*
Clinical Trials as Topic
Humans
Hydroxychloroquine / therapeutic use
Internet
Research Design

Substances

Hydroxychloroquine