Transanal endoluminal repair for anastomotic leakage after low anterior resection

BMC Surg. 2022 Jan 26;22(1):24. doi: 10.1186/s12893-022-01484-4.

Abstract

Background: There is still no consensus on the management of colorectal anastomotic leakage after low anterior resection. The goal was to evaluate the outcomes of patients who underwent transanal endoluminal repair + laparoscopic drainage ± stoma vs. drainage only ± stoma.

Methods: Retrospective chart review of patients sustaining anastomotic leakage after laparoscopic low anterior resection between January 2013 and September 2020 who required laparoscopic reoperation.

Results: Forty-nine patients were included, 22 patients underwent combined laparoscopy and transanal endoluminal repair and 27 patients had drainage with a stoma (n = 16) or drainage alone (n = 11), without direct anastomotic repair. The overall morbidity rate was 30.6% and the mortality rate was 2%. Combined laparoscopic lavage/drainage and transanal endoluminal repair of anastomotic leakage was associated with a lower complication rate (13.6% vs. 44.4%, p = 0.03) and fewer intraabdominal infections (4.5% vs. 29.6%, p = 0.03) compared with no repair.

Conclusions: Combined laparoscopic lavage/drainage and transanal endoluminal repair is effective in the management of colorectal anastomosis leakage and was associated with lower morbidity-in particular intraabdominal infection-compared with no repair. However, our results need to be confirmed in larger, and ideally randomized, studies.

Keywords: Anastomosis leakage; Colorectal anastomosis; Low anterior resection; Transanal endoluminal repair.

MeSH terms

  • Anastomosis, Surgical* / methods
  • Anastomotic Leak* / etiology
  • Anastomotic Leak* / surgery
  • Angioplasty
  • Humans
  • Laparoscopy
  • Proctectomy* / adverse effects
  • Retrospective Studies