Lens Epithelial Cell Removal in Routine Phacoemulsification: Is It Worth the Bother?

Am J Ophthalmol. 2022 Jul:239:1-10. doi: 10.1016/j.ajo.2022.01.013. Epub 2022 Jan 23.

Abstract

Purpose: To review the literature on crystalline lens epithelial cell (LEC) removal in routine phacoemulsification and determine whether it should be incorporated as part of a surgeon's standard technique.

Design: Perspective.

Methods: Expert commentary with video demonstrations on techniques of removal of LECs and associated potential complications. Discussion incorporates the importance of LEC removal, a review of techniques to prevent posterior capsular opacification (PCO), and the effects of intraocular lens design on LEC proliferation and PCO.

Results: The evidence suggests that LEC removal should be routinely performed as it can be carried out safely and with considerable short- and long-term benefits for patients. With effective cleanup, there is reduced anterior capsule opacification, fibrosis, and decentration of the capsular bag as well as reduced rates of posterior capsular opacification. Techniques for removal are easy to learn, with very low complication rates, and can reduce the risk of the long-term need for technically complex procedures such as intraocular lens explantation.

Conclusions: LEC removal from both the anterior and posterior capsule is part of a continuous, incremental improvement of cataract surgery and should be introduced to ophthalmology trainees during their formative years as part of their regular cataract surgery armamentarium.

Publication types

  • Review

MeSH terms

  • Capsule Opacification* / surgery
  • Cataract* / etiology
  • Epithelial Cells
  • Humans
  • Lens Capsule, Crystalline* / surgery
  • Lenses, Intraocular* / adverse effects
  • Phacoemulsification* / adverse effects
  • Postoperative Complications / prevention & control
  • Postoperative Complications / surgery