Struct-f4: a Rcpp package for ancestry profile and population structure inference from f4-statistics

Pablo Librado; Ludovic Orlando

doi:10.1093/bioinformatics/btac046

Struct-f4: a Rcpp package for ancestry profile and population structure inference from f4-statistics

Bioinformatics. 2022 Mar 28;38(7):2070-2071. doi: 10.1093/bioinformatics/btac046.

Authors

Pablo Librado¹, Ludovic Orlando¹

Affiliation

¹ Centre for Anthropobiology and Genomics of Toulouse, CNRS UMR 5288, Université de Toulouse, Université Paul Sabatier, 31000 Toulouse, France.

Abstract

Summary: Visualization and inference of population structure is increasingly important for fundamental and applied research. Here, we present Struct-f4, providing automated solutions to characterize and summarize the genetic ancestry profile of individuals, assess their genetic affinities, identify admixture sources and quantify admixture levels.

Availability and implementation: Struct-f4 is written in Rcpp and relies on f4-statistics and Markov Chain Monte Carlo (MCMC) optimization. It is freely available under GNU General Public License in Bitbucket (https://bitbucket.org/plibradosanz/structf4/).

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Markov Chains
Monte Carlo Method
Software*