Crystal structure and Hirshfeld surface analysis of 2,2,2-tri-fluoro-1-(7-methyl-imidazo[1,2- a]pyridin-3-yl)ethan-1-one

Acta Crystallogr E Crystallogr Commun. 2022 Jan 1;78(Pt 1):12-17. doi: 10.1107/S2056989021012676.

Abstract

The bicyclic imidazo[1,2-a]pyridine core in the mol-ecule of the title compound, C10H7F3N2O, is planar within 0.004 (1) Å. In the crystal, the mol-ecules are linked by pairs of C-H⋯N and C-H⋯O hydrogen bonds, forming strips. These strips are connected by the F⋯F contacts into layers, which are further joined by π-π stacking inter-actions. The Hirshfeld surface analysis and fingerprint plots reveal that mol-ecular packing is governed by F⋯H/H⋯F (31.6%), H⋯H (16.8%), C⋯H/H⋯C (13.8%) and O⋯H/H⋯O (8.5%) contacts.

Keywords: F⋯F contacts; Hirshfeld surface analysis; crystal structure; hydrogen bonds; imidazo[1,2-a]pyridine.