Genes Interacting with Fluorides and Their Impact on Caries Susceptibility and Erosive Tooth Wear

Abstract

The use of fluorides to address dental caries experience in populations was one of the biggest successes of public health in the twentieth century. The widespread use of fluorides also brought fluorosis to areas that otherwise would not be affected. This chapter briefly discusses the impact of fluorides on dental caries and amelogenesis and emphasizes the impact of fluorides on genes that are relevant to amelogenesis, dental caries, erosive tooth wear, and fluorosis.