Acute liver injury following short-term use of the herbal supplement kratom

Abstract

Kratom, a tropical plant and dietary supplement with dose-dependent effects, has physiologic effects similar to opioids as well as stimulant effects. Kratom, like all dietary supplements, is not regulated in the United States and its effects have raised potential and safety concerns. This article describes a patient who presented to the ED with jaundice and acute liver injury, which after a thorough exclusion of alternative causes was attributed to kratom use.