Clinical Features and Neurodevelopmental Outcomes for Infants with Perinatal Vertical Transmission of Zika Virus, Colombia

Emerg Infect Dis. 2022 Feb;28(2):453-456. doi: 10.3201/eid2802.204551.

Abstract

Transplacental transmission of Zika virus has been reported during all trimesters of pregnancy and might lead to central nervous system anomalies, including microcephaly. We report 3 cases of perinatal Zika infection identified during the epidemic in Colombia and provide detailed descriptions of clinical features, diagnosis, and neurodevelopmental outcome at 18 months of age (corrected).

Keywords: Colombia; Zika virus; clinical features; infants; neurodevelopment; newborns; perinatal infection; vector-borne infections; vertical transmission; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Colombia / epidemiology
  • Female
  • Humans
  • Infant
  • Infectious Disease Transmission, Vertical
  • Microcephaly* / epidemiology
  • Microcephaly* / etiology
  • Pregnancy
  • Pregnancy Complications, Infectious*
  • Zika Virus Infection* / diagnosis
  • Zika Virus Infection* / epidemiology
  • Zika Virus*