Successful rapid desensitization to atezolizumab in delayed hypersensitivity confirmed with lymphocyte transformation test

Margarita Giraldo-Tugores; Carlos Fernández-Lozano; Alejandra Carrón-Herrero; Pablo Gajate; Javier Martinez-Botas; Cristina Pueyo-López; Emilio Solano-Solares; María Pilar Berges-Gimeno

doi:10.1016/j.jaip.2021.12.041

Successful rapid desensitization to atezolizumab in delayed hypersensitivity confirmed with lymphocyte transformation test

J Allergy Clin Immunol Pract. 2022 Jun;10(6):1649-1651. doi: 10.1016/j.jaip.2021.12.041. Epub 2022 Jan 21.

Authors

Margarita Giraldo-Tugores¹, Carlos Fernández-Lozano², Alejandra Carrón-Herrero³, Pablo Gajate⁴, Javier Martinez-Botas⁵, Cristina Pueyo-López⁶, Emilio Solano-Solares⁷, María Pilar Berges-Gimeno⁸

Affiliations

¹ Allergology Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain. Electronic address: mgiraltug@gmail.com.
² Biochemistry Research Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain; Alcalá University, Madrid, Spain.
³ Allergology Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain.
⁴ Medical Oncology Department, Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria and Centro de Investigación Biomédica en Red Cáncer, Madrid, Spain.
⁵ Biochemistry Research Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain; Biochemistry Research Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria and Centro de Investigación Biomédica en Red Cáncer, Madrid, Spain.
⁶ Pharmacy Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
⁷ Allergology Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain. Electronic address: emilio.solano.solares@gmail.com.
⁸ Allergology Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain; Redes de Investigación Cooperativa Orientadas a Resultados en Salud, Madrid, Spain. Electronic address: berges.pilar@gmail.com.

PMID: 35074597
DOI: 10.1016/j.jaip.2021.12.041

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Monoclonal, Humanized
Desensitization, Immunologic
Drug Hypersensitivity* / diagnosis
Drug Hypersensitivity* / therapy
Humans
Hypersensitivity, Delayed*
Lymphocyte Activation

Substances

Antibodies, Monoclonal, Humanized
atezolizumab