Comparison of perioperative outcomes of robotic-assisted versus video-assisted thoracoscopic right upper lobectomy in non-small cell lung cancer

Jia Huang; Yu Tian; Qian-Jun Zhou; Jun-Wei Ning; Ze-Nan Gu; Pei-Ji Lu; Jian-Tao Li; Hao Lin; Tian-Xiang Chen; Yun-Hai Yang; Min P Kim; Robert E Merritt; Marco Ghisalberti; Long Jiang; Qing-Quan Luo

doi:10.21037/tlcr-21-960

Comparison of perioperative outcomes of robotic-assisted versus video-assisted thoracoscopic right upper lobectomy in non-small cell lung cancer

Transl Lung Cancer Res. 2021 Dec;10(12):4549-4557. doi: 10.21037/tlcr-21-960.

Authors

Jia Huang^#¹, Yu Tian^#¹, Qian-Jun Zhou^#¹, Jun-Wei Ning¹, Ze-Nan Gu¹, Pei-Ji Lu¹, Jian-Tao Li¹, Hao Lin¹, Tian-Xiang Chen¹, Yun-Hai Yang¹, Min P Kim², Robert E Merritt³, Marco Ghisalberti⁴, Long Jiang¹, Qing-Quan Luo¹

Affiliations

¹ Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
² Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX, USA.
³ Division of Thoracic Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
⁴ Thoracic Surgery Unit, University Hospital of Siena, Siena, Italy.

^# Contributed equally.

Abstract

Background: Robotic-assisted thoracic surgery (RATS) has been widely used in the treatment of lung cancer. The perioperative outcomes of right upper lobectomy (RUL) using RATS and video-assisted thoracic surgery (VATS) were retrospectively investigated and compared. We aimed to summarize a single-center experience of RATS and 4-port unidirectional VATS in RUL, and to discuss the safety and the essentials of the surgery.

Methods: We retrospectively analyzed the 685 with non-small cell lung cancer (NSCLC) patients who underwent minimally invasive RUL in our center by the same surgical group from January 2015 to December 2019. Both RATS and VATS were performed with three ports with utility incision. The 685 participants were divided into RATS (335 cases) and VATS (350 cases) groups according to surgical method. Baseline characteristics and perioperative outcomes including dissected lymph nodes, postoperative duration of drainage, postoperative hospital stay, and incidence of postoperative complications were compared between the groups.

Results: In the 685 patients enrolled, the baseline characteristics were comparable, and no postoperative 30-day mortality or intraoperative blood transfusion were observed. Compared with VATS, RATS had less surgical duration (90.22±12.16 vs. 92.68±12.26 min, P<0.001), less length of stay (4.71±1.37 vs. 5.26±1.56 days, P<0.001), and decreased postoperative duration of drainage (3.49±1.15 vs. 4.09±1.57 days, P<0.001). No significant difference was observed in the lymph nodes dissection, blood loss, conversion rate and morbidities. The cost of RATS was much higher than VATS (85,329.41±12,893.44 vs. 68,733.43±14,781.32 CNY, P<0.001).

Conclusions: Robot assisted RUL had similar perioperative outcomes compared to VATS RUL lobectomy using similar three port with utility incision technique. The advantages of RATS included finer dissection of lymph node, relatively less operation time, earlier chest tube removal and discharge.

Keywords: Lobectomy; non-small cell lung cancer (NSCLC); robotic; video-assisted thoracic surgery (VATS).