Steroid responsive inflammatory myofibroblastic tumor of the lung evaluated by FDG PET/CT imaging

James Yuheng Jiang; Monica Comsa; Veronica Chi Ken Wong; Robert Mansberg

doi:10.1016/j.radcr.2021.11.049

Steroid responsive inflammatory myofibroblastic tumor of the lung evaluated by FDG PET/CT imaging

Radiol Case Rep. 2022 Jan 14;17(3):907-910. doi: 10.1016/j.radcr.2021.11.049. eCollection 2022 Mar.

Authors

James Yuheng Jiang¹, Monica Comsa^{2

3}, Veronica Chi Ken Wong^{1

3}, Robert Mansberg^{1

3}

Affiliations

¹ Departments of Nuclear Medicine and PET, Nepean Hospital, Kingswood, Derby St, NSW 2747, Australia.
² Department of Respiratory Medicine, Nepean Hospital, Kingswood, NSW, Australia.
³ Faculty of Medicine and Health, University of Sydney, NSW, Australia.

Abstract

A 68-year-old gentleman was referred for ¹⁸F-FDG PET/CT for a pulmonary mass in the left upper lobe which demonstrated intensely FDG-avid confluent pulmonary consolidation in the left upper lobe (SUV_max 15.1). Histopathologic biopsy of the left upper lobe lung mass was consistent with inflammatory myofibroblastic tumor (IMT). The patient was started on steroid treatment in conjunction with antibiotics. Follow-up FDG PET/CT 3 weeks after commence of treatment showed remarkable response of the IMTs to therapy with much less avid FDG uptake (SUV_max 5.4) and marked improvement in the pulmonary consolidation. Nevertheless, the patient underwent left upper lobe lobectomy due to evidence of persistent cystic disease and malignant potential associated with IMTs. Final histopathology was consistent with IMT with no evidence of malignancy.

Keywords: FDG; PET; inflammatory myofibroblastic tumor; inflammatory pseudotumor.

Publication types

Case Reports