Dynamic PET Imaging Using Dual Texture Features

Front Comput Neurosci. 2022 Jan 7:15:819840. doi: 10.3389/fncom.2021.819840. eCollection 2021.

Abstract

Purpose: This study aims to explore the impact of adding texture features in dynamic positron emission tomography (PET) reconstruction of imaging results. Methods: We have improved a reconstruction method that combines radiological dual texture features. In this method, multiple short time frames are added to obtain composite frames, and the image reconstructed by composite frames is used as the prior image. We extract texture features from prior images by using the gray level-gradient cooccurrence matrix (GGCM) and gray-level run length matrix (GLRLM). The prior information contains the intensity of the prior image, the inverse difference moment of the GGCM and the long-run low gray-level emphasis of the GLRLM. Results: The computer simulation results show that, compared with the traditional maximum likelihood, the proposed method obtains a higher signal-to-noise ratio (SNR) in the image obtained by dynamic PET reconstruction. Compared with similar methods, the proposed algorithm has a better normalized mean squared error (NMSE) and contrast recovery coefficient (CRC) at the tumor in the reconstructed image. Simulation studies on clinical patient images show that this method is also more accurate for reconstructing high-uptake lesions. Conclusion: By adding texture features to dynamic PET reconstruction, the reconstructed images are more accurate at the tumor.

Keywords: dynamic PET; gray level-gradient cooccurrence matrix (GGCM); gray-level run length matrix (GLRLM); texture feature; tumor.