A novel synthesis, analysis and evaluation of Musa coccinea based zero valent iron nanoparticles for antimicrobial and antioxidant

Tan Phat Chau; Kathirvel Brindhadevi; Ramakrishnan Krishnan; Mansour Ali Alyousef; Hesham S Almoallim; Niwooti Whangchai; Surachai Pikulkaew

doi:10.1016/j.envres.2022.112770

A novel synthesis, analysis and evaluation of Musa coccinea based zero valent iron nanoparticles for antimicrobial and antioxidant

Environ Res. 2022 Jun:209:112770. doi: 10.1016/j.envres.2022.112770. Epub 2022 Jan 19.

Authors

Tan Phat Chau¹, Kathirvel Brindhadevi², Ramakrishnan Krishnan³, Mansour Ali Alyousef⁴, Hesham S Almoallim⁵, Niwooti Whangchai⁶, Surachai Pikulkaew⁷

Affiliations

¹ Institute of Applied Science & Technology, Van Lang University, Ho Chi Minh, 70000, Viet Nam. Electronic address: phat.ct@vlu.edu.vn.
² Center for Transdisciplinary Research (CFTR), Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
³ Department of Business, Harrisburg University of Science and Technology, Harrisburg, PA, 17101, USA.
⁴ General Directorate of Health Affairs in Riyadh, Ministry of Health, Saudi Arabia.
⁵ Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, PO Box-60169, Riyadh, 11545, Saudi Arabia.
⁶ Faculty of Fisheries Technology and Aquatic Resources, Maejo University, Chiang Mai, 50290, Thailand.
⁷ Research Center of Producing and Development of Products and Innovations for Animal Health and Production, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand; Department of Food Animal Clinic, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand. Electronic address: surapikulkaew@gmail.com.

PMID: 35063432
DOI: 10.1016/j.envres.2022.112770

Abstract

Zerovalent Iron Nanoparticles (MC-ZVI NPs) were synthesized from Musa coocinea peel extract as reducing and stabilizing agent using a novel synthesis technique. The synthesis of MC-ZVI NPs was confirmed using UV-vis spectroscopy showing a sharp absorption peak at 341 nm. Further the chemical and structural characterization of MC-ZVI NPs were performed using Fourier Transform Infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), and Dynamic Light Scattering technique (DLS). FTIR analysis revealed the presence of phytochemical molecules associated with the MC-ZVI NPs. SEM analysis revealed the synthesized MC-ZVI NPs were in spherical shaped, while DLS analysis confirmed the synthesis of poly dispersed and non-homogenous MC-ZVI NPs. The antimicrobial efficacy of MC-ZVI NPs synthesized using Musa coccinea peel extract was tested against bacterial (Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Bacillus subtilis) and fungal (Aspergillus niger) pathogens. But MC-ZVI NPs exhibited maximum of 19 mm zone of inhibition against B. subtilis and A. niger. Further the free radical scavenging activity MC-ZVI NPs was confirmed using DPPH, hydroxyl radical, hydrogen peroxide, FRAP assay showing displayed effective antioxidant activity. Thus, the present idea will give a fast and cost effective approach to synthesize MC-ZVI NPs with antimicrobial property for application in biomedical purposes.

Keywords: Antimicrobial; Antioxidant; Hydrogen peroxide; Musa coccinea; Zero valent iron.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology
Anti-Infective Agents* / pharmacology
Antioxidants / pharmacology
Bacillus subtilis
Iron / chemistry
Metal Nanoparticles* / chemistry
Microbial Sensitivity Tests
Musa*
Spectroscopy, Fourier Transform Infrared

Substances

Anti-Bacterial Agents
Anti-Infective Agents
Antioxidants
Iron