Clinical Profile and Renal Ultrasound Characteristics of Children With Nutcracker Syndrome in Turkey

Indian Pediatr. 2022 Jan 15;59(1):28-30.

Abstract

Objective: We aimed to evaluate the clinical profile and radiological findings of children with nutcracker syndrome (NCS) and to assess the association between the parameters.

Methods: A retrospective analysis of the clinical, laboratory and radiological parameters of children diagnosed with NCS between January, 2011 and October, 2017 was done.

Results: Of a total of 29 patients [19 girls, 65.5%] with NCS, having a mean (SD) age of 10.8 years, 72.4% had BMI <-2SD. Approximately half of the patients (51.7%) were asymptomatic. Left flank pain was commonest (9/29; 31%) symptom, followed by macroscopic hematuria (4/29; 13.8%). Isolated proteinuria was seen in 9 children. There was no significant difference between the symptomatic and asymptomatic patients in terms of Doppler ultrasonography findings. All patients were followed up conservatively, 5 received enalapril therapy for moderate proteinuria.

Conclusion: NCS should be considered in children, especially with low BMI, presenting with orthostatic proteinuria and hematuria, with or without left flank pain after ruling out the common causes.

MeSH terms

  • Child
  • Female
  • Humans
  • Renal Nutcracker Syndrome* / diagnostic imaging
  • Renal Veins / diagnostic imaging
  • Retrospective Studies
  • Turkey / epidemiology
  • Ultrasonography