Solvothermal synthesis of silver tungstate integrated with carbon nitrides matrix composites for highly sensitive electrochemical nitrofuran derivative sensing in biological samples

Abstract

In the present research, we aimed to develop a novel electrochemical method based on transition metal tungstate nanorods incorporated sulfur doped carbon nitrides matrix (Ag₂WO₄@SGCN) for determination of antibiotic drug. The morphological and structural analysis of the prepared Ag2WO4@SGCN were performed by various techniques including SEM, EDS, XRD, and EIS. Under the optimal conditions of the sensor, the Ag₂WO₄@SGCN modified electrode showed outstanding electrocatalytic performance toward the electro-reduction of nitrofurantoin (NFT) with a significant increase in cathodic peak currents in comparison with the bare electrode. By differential pulse voltammetric (DPV) method the fabricated nitrofurantoin sensor gave linear response in the concentration range from 0.005 to 935 μM with detection limit (3Sb/m) of 0.0013 μM. Importantly, the practically of the proposed Ag₂WO₄@SGCN modified electrode was demonstrated in different biological samples. In addition, Ag₂WO₄@SGCN electrode displayed excellent anti-interfering ability and repeatability, reproducibility, storage and operational stability has been successfully demonstrated for detection of NFT.

Keywords: Antibiotic drug; Carbon nitrides matrix; Electrocatalyst; Electrochemical determination; Transition metal tungstate.