Preservation of Mimosa tenuiflora Antiaflatoxigenic Activity Using Microencapsulation by Spray-Drying

Molecules. 2022 Jan 13;27(2):496. doi: 10.3390/molecules27020496.

Abstract

Mimosa tenuiflora aqueous extract (MAE) is rich in phenolic compounds. Among them, condensed tannins have been demonstrated to exhibit a strong antioxidant and antiaflatoxin B1 activities in Aspergillus flavus. Since antioxidant capacity can change with time due to environmental interactions, this study aimed to evaluate the ability of encapsulation by spray-drying of Mimosa tenuiflora aqueous extract to preserve their biological activities through storage. A dry formulation may also facilitate transportation and uses. For that, three different wall materials were used and compared for their efficiency. Total phenolic content, antioxidant activity, antifungal and antiaflatoxin activities were measured after the production of the microparticles and after one year of storage at room temperature. These results confirmed that encapsulation by spray-drying using polysaccharide wall materials is able to preserve antiaflatoxin activity of Mimosa tenuiflora extract better than freezing.

Keywords: antiaflatoxin activity; antioxidant activity; encapsulation; polysaccharides; spray-drying.

MeSH terms

  • Aflatoxin B1 / antagonists & inhibitors*
  • Antifungal Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Aspergillus flavus / drug effects
  • Aspergillus flavus / growth & development
  • Drug Compounding / methods*
  • Drug Storage
  • Microscopy, Electron, Scanning
  • Mimosa / chemistry*
  • Particle Size
  • Phenols / analysis
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology*
  • Polysaccharides / chemistry
  • Powders / analysis
  • Powders / chemistry
  • Spray Drying*

Substances

  • Antifungal Agents
  • Antioxidants
  • Phenols
  • Plant Extracts
  • Polysaccharides
  • Powders
  • Aflatoxin B1