Contemporary Molecular Analyses of Malignant Tumors for Precision Treatment and the Implication in Oral Squamous Cell Carcinoma

Julia Yu Fong Chang; Chih-Huang Tseng; Pei Hsuan Lu; Yi-Ping Wang

doi:10.3390/jpm12010012

Contemporary Molecular Analyses of Malignant Tumors for Precision Treatment and the Implication in Oral Squamous Cell Carcinoma

J Pers Med. 2021 Dec 28;12(1):12. doi: 10.3390/jpm12010012.

Authors

Julia Yu Fong Chang^{1

2

3}, Chih-Huang Tseng^{1

4

5}, Pei Hsuan Lu^{1

2}, Yi-Ping Wang^{1

2

3}

Affiliations

¹ Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei 10617, Taiwan.
² Department of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 10617, Taiwan.
³ Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei 10617, Taiwan.
⁴ Division of Oral Pathology & Maxillofacial Radiology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
⁵ Division Oral & Maxillofacial Imaging Center, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

Abstract

New molecular tests and methods, in addition to morphology-based diagnosis, are widely used as a new standard of care in many tumors. "One-size-fits-all medicine" is now shifting to precision medicine. This review is intended to discuss the key steps toward to development of precision medicine and its implication in oral squamous cell carcinoma. The challenges and opportunities of precision medicine in oral cancer will be sequentially discussed based on the four steps of precision medicine: identification/detection, diagnosis, treatment and monitoring.

Keywords: oral squamous cell carcinoma; personalized medicine; therapy.

Publication types

Review

Abstract

Publication types

Grants and funding