Aripiprazole-Induced Oculogyric Crisis: A Pediatric Case Series and A Brief Narrative Review

Children (Basel). 2021 Dec 29;9(1):22. doi: 10.3390/children9010022.

Abstract

Oculogyric crisis (OGC) represent an unusual type of dystonic movement disorder, usually reported as an adverse event of antipsychotic drugs, with acute or tardive onset, likely due to a functional disruption of dopaminergic neurotransmission. It is seldom reported in children with aripiprazole, an atypical antipsychotic commonly used in youths. In this manuscript, we report on a case series of three pediatric patients and provide a brief narrative review of the literature, in order to increase the awareness of clinicians and to foster future research in this area.

Keywords: aripiprazole; extrapyramidal effects; oculogyric crisis; pediatric.

Publication types

  • Case Reports