Genome Editing among Bioethics and Regulatory Practices

Biomolecules. 2021 Dec 22;12(1):13. doi: 10.3390/biom12010013.

Abstract

In the last decade, genome editing technologies became very effective and several clinical trials have been started in order to use them for treating some genetic diseases. Interestingly, despite more than 50 years of discussion about the frontiers of genetics in human health and evolution, the debate about the bioethics and the regulatory practices of genome editing is still far from satisfactory answers. This delay results from an excessive emphasis on the effectiveness of the genome editing technologies that is relevant for the regulatory practices, but not at a bioethical level. Indeed, other factors (such as accessibility and acceptability) could make these techniques not accepted at the bioethical level, even in the presence of their 100% effectiveness.

Keywords: bioethics; genome editing; regulatory practices.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Bioethics / history*
  • CRISPR-Cas Systems*
  • Gene Editing / ethics*
  • Gene Editing / history
  • History, 20th Century
  • History, 21st Century
  • Humans