Pydiflumetofen Co-Formulated with Prothioconazole: A Novel Fungicide for Fusarium Head Blight and Deoxynivalenol Control

Toxins (Basel). 2022 Jan 3;14(1):34. doi: 10.3390/toxins14010034.

Abstract

Fusarium head blight (FHB) is an important disease of small grain cereals worldwide, resulting in reduced yield and quality as well as the contamination of harvested grains with mycotoxins. The key mycotoxin of concern is deoxynivalenol (DON), which has legislative and advisory limits in numerous countries. Cereal growers have a number of control options for FHB including rotation, cultivation, and varietal resistance; however, growers are still reliant on fungicides applied at flowering as part of an IPM program. Fungicides currently available to control FHB are largely restricted to triazole chemistry. This study conducted three field experiments to compare a new co-formulation of pydiflumetofen (a succinate dehydrogenase inhibitor (SDHI) with the tradename ADEPIDYN) and prothioconazole (a triazole) against current standard fungicides at various timings (flag leaf fully emerged, mid-head emergence, early flowering, and late flowering) for the control of FHB and DON. Overall, the co-formulation showed greater efficacy compared to either pydiflumetofen alone or current fungicide chemistry. This greater activity was demonstrated over a wide range of spray timings (flag leaf fully emerged to late flowering). The availability of an SDHI with good activity against FHB and the resulting DON contamination of harvested grain will give growers an additional tool within an IPM program that will provide a greater flexibility of spray application windows and reduce fungicide resistance selection pressure.

Keywords: ADEPIDYN™; Fusarium graminearum; deoxynivalenol; prothioconazole; pydiflumetofen; wheat.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Edible Grain / microbiology
  • Fungicides, Industrial / pharmacology*
  • Fusarium / drug effects*
  • Mycotoxins / biosynthesis*
  • Plant Diseases / prevention & control*
  • Pyrazoles / pharmacology
  • Time Factors
  • Triazoles / pharmacology*
  • Trichothecenes / metabolism*
  • Triticum / microbiology*

Substances

  • Fungicides, Industrial
  • Mycotoxins
  • Pyrazoles
  • Triazoles
  • Trichothecenes