Can AlphaFold2 predict the impact of missense mutations on structure?

Nat Struct Mol Biol. 2022 Jan;29(1):1-2. doi: 10.1038/s41594-021-00714-2.

Authors

Gwen R Buel¹, Kylie J Walters²

Affiliations

¹ Center for Structural Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
² Center for Structural Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA. kylie.walters@nih.gov.

PMID: 35046575
DOI: 10.1038/s41594-021-00714-2

No abstract available

Publication types

Letter
Research Support, N.I.H., Intramural

MeSH terms

Algorithms*
Models, Molecular
Mutation, Missense / genetics*
Protein Domains
Protein Structure, Secondary
Proteins / chemistry*
Proteins / genetics*
Ubiquitin / chemistry

Substances

Proteins
Ubiquitin

Grants and funding

ZIA BC011627/ImNIH/Intramural NIH HHS/United States