[A Case of Polymorphous Low-Grade Adenocarcinoma of the Palate]

Gan To Kagaku Ryoho. 2021 Dec;48(13):1877-1880.
[Article in Japanese]

Abstract

Polymorphous low-grade adenocarcinoma(PLGA)is a relatively rare low-grade adenocarcinoma of the minor salivary glands. If radical resection is performed, the prognosis is favorable. We present the case of a 62-year-old woman who presented to our clinic in April 2019 after noticing a mass on her palate. The intraoral examination revealed a 10-mm-diameter, well-defined, tender mass extending from the right hard palate to the soft palate. We suspected a benign tumor originating from the area of transition between the hard and soft palates. An excisional biopsy of the mass was performed, and PLGA was diagnosed on the basis of histopathologic findings. In May 2019, the tumor was resected under general anesthesia and a soft palatal lift prosthesis was applied for functional recovery. In July 2020, the soft palate defect was repaired using an ulnar forearm free flap during a two-stage reconstruction procedure. The patient developed complete necrosis of the free flap, and the defect was re-reconstructed using a buccinator-based myomucosal flap. There was no evidence of disease recurrence or metastasis. Two years have passed since the initial surgery, and the patient's clinical course has been well so far.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma*
  • Female
  • Humans
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Palate
  • Salivary Gland Neoplasms*
  • Surgical Flaps