Stereopsis after corneal refractive surgeries: a systematic review and meta-analysis

Abstract

Purpose: To systematically review the published manuscripts on stereopsis after corneal refractive surgery.

Methods: The Web of Science, PubMed, Scopus, ProQuest, Clinical Key, Embase, and Cochrane Library were searched for relevant articles published until August 2020. The fixed- or random-effects models were used to estimate the Weighted mean difference (WMD) or Relative risk (RR) and 95% Confidence interval (CI) for postoperative stereopsis changes and incidence when applicable. Meta-regression was conducted for adjusting the effects of potential confounders.

Results: Seven studies (1266 eyes) in adults and ten studies in pediatrics (259 eyes) were included. In adults, stereopsis improved significantly compared to the preoperative state (WMD = - 27.4, 95% CI = - 40.0, - 14.7; I² = 97.8%; P < 0.001). In pediatrics, proportion of patients with stereoacuity postoperatively was 2.18 times compared to preoperative evaluation. (RR = 2.18, 95% CI = 1.2, 3.9; I² = 68.6%, P < 0.001).

Conclusions: Stereopsis improves after corneal refractive surgery in adults and pediatrics.

Keywords: Corneal surgery; Refractive surgery; Stereoacuity; Stereopsis.