Curcumin and curcumoids: hepatoprotection or hepatotoxicity?

Rev Esp Enferm Dig. 2022 May;114(5):304-305. doi: 10.17235/reed.2022.8588/2022.

Abstract

Curcumin (Curcuma longa) and curcumin analogues are plant-based drugs used because of their possible antioxidant and anti-inflammatory. Clinical data on the efficacy of curcumin as a hepatoprotectant are limited, with growing concern for formulations that may potentially increase curcumin hepatotoxicity.

MeSH terms

  • Anti-Inflammatory Agents
  • Antioxidants / adverse effects
  • Chemical and Drug Induced Liver Injury* / etiology
  • Chemical and Drug Induced Liver Injury* / prevention & control
  • Curcumin* / adverse effects
  • Humans
  • Plant Extracts

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Plant Extracts
  • Curcumin