Management of Recurrent Myocarditis Due to Desmoplakin Cardiomyopathy: Diagnostic and Therapeutic Challenges

Malik Ghawanmeh; Blanca Simon Frances; Ajay Kerai; Parth Patel; Jonathan Du; Preetham Kumar

doi:10.1016/j.jaccas.2021.10.005

Management of Recurrent Myocarditis Due to Desmoplakin Cardiomyopathy: Diagnostic and Therapeutic Challenges

JACC Case Rep. 2022 Jan 5;4(1):59-62. doi: 10.1016/j.jaccas.2021.10.005.

Authors

Malik Ghawanmeh¹, Blanca Simon Frances¹, Ajay Kerai¹, Parth Patel¹, Jonathan Du¹, Preetham Kumar¹

Affiliation

¹ MedStar Washington Hospital Center, Washington, DC, USA.

Abstract

We present the case of a 25-year-old woman with desmoplakin cardiomyopathy-related myocarditis. Her high-sensitivity troponin and symptoms improved with pulse steroid therapy and mycophenolate mofetil. The literature lacks data to effectively guide the management of recurrent myocarditis in desmoplakin cardiomyopathy. (Level of Difficulty: Advanced.).

Keywords: DSP, desmoplakin; LGE, late gadolinium enhancement; LV, left ventricular; desmoplakin cardiomyopathy; genetic cardiomyopathy; late gadolinium enhancement; myocarditis.

Publication types

Case Reports