Advances in microfluidics devices and its applications in personalized medicines

Prog Mol Biol Transl Sci. 2022;186(1):191-201. doi: 10.1016/bs.pmbts.2021.07.012. Epub 2021 Aug 12.

Abstract

Microfluidics is an exponentially growing area and is being used for numerous applications from basic science to advanced biotechnology and medicines. Microfluidics provides a platform to the research community for studying and building new strategies for the diagnosis and therapeutics applications. In the last decade, microfluidic have enriched the field of diagnostics by providing new solutions which was not possible with conventional detection and treatment methods. Microfluidics has the ability to precisely control and perform high-throughput functions. It has been proven as an efficient and rapid method for biological sample preparation, analysis and controlled drug delivery system. Microfluidics plays significant role in personalized medicine. These personalized medicines are used for medical decisions, practices and other interventions as well as for individual patients based on their predicted response or risk of disease. This chapter highlights microfluidics in developing personalized medical applications for its applications in diseases such as cancer, cardiovascular disease, diabetes, pulmonary disease and several others.

Keywords: Disease; Drugs; Microfluidics devices; Personalized medicine; Translational sciences.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Delivery Systems
  • Humans
  • Lab-On-A-Chip Devices
  • Microfluidics*
  • Neoplasms*
  • Precision Medicine