The impact of motion artifacts on quantitative optical coherence tomography angiography analysis in Parkinson's disease

Mahdy Ranjbar; Pauline Plöttner; Jan A M Sochurek; Jost L Lauermann; Florian Alten; Jannik Prasuhn; Meike Kasten; Norbert Brüggemann

doi:10.1016/j.parkreldis.2022.01.006

The impact of motion artifacts on quantitative optical coherence tomography angiography analysis in Parkinson's disease

Parkinsonism Relat Disord. 2022 Feb:95:57-58. doi: 10.1016/j.parkreldis.2022.01.006. Epub 2022 Jan 10.

Authors

Mahdy Ranjbar¹, Pauline Plöttner², Jan A M Sochurek³, Jost L Lauermann⁴, Florian Alten⁴, Jannik Prasuhn⁵, Meike Kasten⁶, Norbert Brüggemann⁵

Affiliations

¹ Department of Ophthalmology, University of Lübeck, Germany; Laboratory for Angiogenesis and Ocular Cell Transplantation, University of Lübeck, Germany. Electronic address: eye.research101@gmail.com.
² Laboratory for Angiogenesis and Ocular Cell Transplantation, University of Lübeck, Germany; Department of Neurology, University of Lübeck, Germany.
³ Laboratory for Angiogenesis and Ocular Cell Transplantation, University of Lübeck, Germany.
⁴ Department of Ophthalmology, University of Münster, Germany.
⁵ Department of Neurology, University of Lübeck, Germany; Institute of Neurogenetics, University of Lübeck, Germany; Center for Brain, Behavior and Metabolism (CBBM), University of Lübeck, Germany.
⁶ Institute of Neurogenetics, University of Lübeck, Germany; Department of Psychiatry and Psychotherapy, University of Lübeck, Germany.

PMID: 35032741
DOI: 10.1016/j.parkreldis.2022.01.006

Abstract

We have previously shown that OCTA imaging in PD patients can be challenging. Our data suggest that retinal perfusion is reduced in both plexuses in PD, which may serve as a noninvasive biomarker in the future. Yet, control of motion artifacts in OCTA measurements is critical in this motor-impaired cohort.

Keywords: Biomarker; Image artifacts; OCTA; Parkinson's disease; Retina.

Publication types

Letter

MeSH terms

Angiography
Artifacts
Humans
Parkinson Disease* / diagnostic imaging
Retina
Tomography, Optical Coherence* / methods