Two distinct stem cell-like subtypes of hepatocellular carcinoma with clinical significance and their therapeutic potentials

Affiliations

• ¹ Department of Systems Biology, the University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
• ² Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
• ³ Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, 13496, Republic of Korea.
• ⁴ Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
• ⁵ Department of Surgery, Yonsei University Health System, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
• ⁶ Division of Thoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, 77030, USA.
• ⁷ Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 55902, USA.
• ⁸ Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, 02841, Republic of Korea.
• ⁹ Department of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.