Amplitude-integrated EEG recorded at 32 weeks postconceptional age. Correlation with MRI at term

J Perinatol. 2022 Jul;42(7):880-884. doi: 10.1038/s41372-021-01295-0. Epub 2022 Jan 15.

Abstract

Objective: The study aims to establish the role of late aEEG (scored by Burdjalov) in predicting brain maturation as well as abnormalities evaluated at term equivalent age (TEA) by brain MRI.

Methods: 91 infants born before 30 wks gestation underwent an aEEG monitoring at 32 wks postconceptional age (PCA). aEEG, was correlated with TEA MRI, scored by Kidokoro.

Results: A significant correlation between the aEEG score and the MRI scores was found. The same results were obtained for the aEEG continuity score; cyclicity and bandwidth scores were associated with grey matter and cerebellar MRI items. Moreover, a correlation between aEEG and cEEG recorded both at 32 and 40 wks PCA, was found.

Conclusions: aEEG monitoring can be predictive of MRI findings at TEA, suggesting that it could be implemented as a useful tool to support ultrasound to help identify neonates who will benefit from early intervention services.

MeSH terms

  • Brain / diagnostic imaging
  • Electroencephalography* / methods
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature*
  • Magnetic Resonance Imaging / methods
  • Neuroimaging