Newly diagnosed type 1 diabetes in a 93 year old

BMJ Case Rep. 2022 Jan 13;15(1):e246799. doi: 10.1136/bcr-2021-246799.

Abstract

Type 1 diabetes is typically a disease of young but can present at any age. We present a case of a 93-year-old woman who presented with 10 days history of feeling lethargic, polydipsia and decreased appetite. Her capillary blood glucose was raised at 25 mmol/L with significant ketonaemia and venous blood gas showing metabolic acidosis. She had a background of primary hypothyroidism and vitamin B12 deficiency with weakly positive parietal cell antibodies. Laboratory investigations confirmed diabetes with HbA1c of 117 mmol/mol (12.9%). In view of high clinical suspicion of type 1 diabetes, her diabetes autoantibodies were checked which showed strongly positive anti-GAD antibody with titre of >2000 IU/mL (range<10) confirming our diagnosis. She was treated with diabetic ketoacidosis protocol with intravenous fluids and intravenous insulin. On recovery, she was discharged home on once daily insulin with aim to self-manage diabetes with support from district nurses and to avoid hypoglycaemia.

Keywords: diabetes; drugs and medicines; healthcare improvement and patient safety.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Autoantibodies
  • Diabetes Mellitus, Type 1* / complications
  • Diabetes Mellitus, Type 1* / diagnosis
  • Diabetes Mellitus, Type 1* / drug therapy
  • Diabetic Ketoacidosis* / diagnosis
  • Diabetic Ketoacidosis* / drug therapy
  • Female
  • Humans
  • Hypoglycemia*
  • Insulin

Substances

  • Autoantibodies
  • Insulin