Benign Parathyroid Hyperplasia With Incidental Pulmonary Seeding on 99mTc-MIBI Scintigraphy and FDG PET/CT

Clin Nucl Med. 2022 Mar 1;47(3):e329-e330. doi: 10.1097/RLU.0000000000004011.

Abstract

A 50-year-old woman with end-stage renal disease presented with recurrent hyperparathyroidism after parathyroidectomy. 99mTc-MIBI scintigraphy did not show MIBI-avid lesion in the neck or mediastinum but in bilateral lung fields instead. On suspicion of malignancy, 18F-FDG PET/CT was performed and depicted no significant FDG uptake throughout the whole body. After resection of the pulmonary nodules, the final histopathology revealed benign parathyroid hyperplasia with pulmonary seeding, which is exceptionally a rare entity.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Hyperplasia / diagnostic imaging
  • Lung
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Parathyroid Glands / diagnostic imaging
  • Positron Emission Tomography Computed Tomography*
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • Technetium Tc 99m Sestamibi