Bone Tuberculous Granulomatous Inflammation Mimicking Malignancy on 68Ga-FAPI PET/CT

Clin Nucl Med. 2022 Apr 1;47(4):348-349. doi: 10.1097/RLU.0000000000003990.

Abstract

A 50-year-old woman presented with back pain for 1 month. Chest CT showed osteolytic destruction of T6 vertebral body. A malignancy was suspected. The patient was subsequently enrolled in the clinical trial of 68Ga-FAPI PET/CT. 68Ga-FAPI PET/CT revealed multiple bone destruction with increased FAPI activity. It was also highly suggestive of malignancy or metastases. However, pathological examination after T6 vertebral surgery confirmed the diagnosis of tuberculous granulomatous inflammation.

Publication types

  • Case Reports

MeSH terms

  • Bone Neoplasms*
  • Female
  • Humans
  • Inflammation / diagnostic imaging
  • Middle Aged
  • Positron Emission Tomography Computed Tomography
  • Quinolines*

Substances

  • 68Ga-FAPI
  • Quinolines