Multimode Optomechanical Weighting of a Single Nanoparticle

Nano Lett. 2022 Jan 26;22(2):710-715. doi: 10.1021/acs.nanolett.1c03890. Epub 2022 Jan 12.

Abstract

We demonstrate multimode optomechanical sensing of individual nanoparticles with a radius between 75 and 150 nm. A semiconductor optomechanical disk resonator is optically driven and detected under ambient conditions, as nebulized nanoparticles land on it. Multiple mechanical and optical resonant signals of the disk are tracked simultaneously, providing access to several pieces of physical information about the landing analyte in real time. Thanks to a fast camera registering the time and position of landing, these signals can be employed to weight each nanoparticle with precision. Sources of error and deviation are discussed and modeled, indicating a path to evaluate the elasticity of the nanoparticles on top of their mere mass. The device is optimized for the future investigation of biological particles in the high megadalton range, such as large viruses.

Keywords: Optomechanical sensor; biosensing; individual nanoparticle; mass spectrometry; multimode analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Nanoparticles*