Neuroscience of Peripheral Nerve Regeneration

Sunil Paramel Mohan; Murugan Ramalingam

doi:10.4103/jpbs.jpbs_182_21

Neuroscience of Peripheral Nerve Regeneration

J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S913-S916. doi: 10.4103/jpbs.jpbs_182_21. Epub 2021 Nov 10.

Authors

Sunil Paramel Mohan^{1

2}, Murugan Ramalingam³

Affiliations

¹ Department of Oral and Maxillofacial Pathology, Sree Anjaneya Institute of Dental Sciences, Kozhikode, Kerala, India.
² Department of Stems Cells and Regenerative Medicine, Malabar Medical College Hospital and Research Centre, Kozhikode, Kerala, India.
³ Biomaterials and Organ Engineering Group Centre for Biomaterials, Cellular and Molecular Theranostics, School of Mechanical Engineering, Vellore Institute of Technology (Deemed to be University), Vellore, Tamil Nadu, India.

Abstract

Peripheral nerve injury involves complex molecular, cellular, and genetic events that help in ultimate regeneration of nerve. Some key factors are upregulated and some downregulated in the process of regeneration of nerve to attain almost perfect architecture. This review renders short overview about how the injured neurons and supporting cells like Schwann cells help in creating ample microenvironment for regeneration of peripheral nerve and their maturation.

Keywords: Nerve regeneration; neuroscience; peripheral nerve.

Publication types

Review