Action selection: Neuropeptidergic gates of behavior

Matthieu Louis; Ilona C Grunwald Kadow

doi:10.1016/j.cub.2021.11.037

Action selection: Neuropeptidergic gates of behavior

Curr Biol. 2022 Jan 10;32(1):R39-R42. doi: 10.1016/j.cub.2021.11.037.

Authors

Matthieu Louis¹, Ilona C Grunwald Kadow²

Affiliations

¹ Neuroscience Research Institute and Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address: mlouis@ucsb.edu.
² Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany; Institute of Physiology II, Faculty of Medicine, University of Bonn, 53115 Bonn, Germany. Electronic address: ilona.grunwald@tum.de.

PMID: 35015994
DOI: 10.1016/j.cub.2021.11.037

Abstract

Nervous systems continuously receive environmental signals with distinct behavioral meanings. To process ambiguous sensory inputs, neural circuits rely on hubs with compartmentalized synaptic structures. A new study has revealed how, in Drosophila larvae, this architecture with the local release of neuropeptides enables the control of flexible and context-dependent behavioral outcomes.

Publication types

Comment

MeSH terms

Animals
Drosophila* / physiology
Larva / physiology
Nervous System
Neuropeptides*

Substances

Neuropeptides

Grants and funding

R01 NS113048/NS/NINDS NIH HHS/United States