Unsprung traps keep PARP inhibitors effective

Nat Cell Biol. 2022 Jan;24(1):2-4. doi: 10.1038/s41556-021-00819-2.

Authors

Peter M Brownlee¹, Luc Provencher¹, Aaron A Goodarzi²

Affiliations

¹ Departments of Biochemistry and Molecular Biology and Oncology, Robson DNA Science Centre, Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
² Departments of Biochemistry and Molecular Biology and Oncology, Robson DNA Science Centre, Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. a.goodarzi@ucalgary.ca.

PMID: 35013555
DOI: 10.1038/s41556-021-00819-2

No abstract available

Publication types

Comment

MeSH terms

Cell Line, Tumor
DNA Repair*
Poly(ADP-ribose) Polymerase Inhibitors* / pharmacology

Substances

Poly(ADP-ribose) Polymerase Inhibitors