Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

ACS Appl Bio Mater. 2021 Aug 16;4(8):5908-5925. doi: 10.1021/acsabm.1c00591. Epub 2021 Jul 19.

Abstract

Cancer is considered one of the leading causes of death, with a growing number of cases worldwide. However, the early diagnosis and efficient therapy of cancer have remained a critical challenge. The emergence of nanomedicine has opened up a promising window to address the drawbacks of cancer detection and treatment. A wide range of engineered nanomaterials and nanoplatforms with different shapes, sizes, and composition has been developed for various biomedical applications. Nanomaterials have been increasingly used in various applications in bioimaging, diagnosis, and therapy of cancers. Recently, numerous multifunctional and smart nanoparticles with the ability of simultaneous diagnosis and targeted cancer therapy have been reported. The multidisciplinary attempts led to the development of several exciting clinically approved nanotherapeutics. The nanobased materials and devices have also been used extensively to develop point-of-care and highly sensitive methods of cancer detection. In this review article, the most significant achievements and latest advances in the nanomaterials development for cancer nanomedicine are critically discussed. In addition, the future perspectives of this field are evaluated.

Keywords: cancer therapy; drug delivery; nanomaterials; nanomedicine; nanoparticles.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Nanomedicine
  • Nanoparticles* / therapeutic use
  • Nanostructures* / therapeutic use
  • Neoplasms* / diagnosis