Claudication due to adventitial cystic degeneration: A differential diagnosis of peripheral artery disease

Vascular. 2023 Jun;31(3):589-593. doi: 10.1177/17085381211068723. Epub 2022 Jan 8.

Abstract

Background: Cystic adventitial disease (CAD) is an important and rare non-atherosclerotic cause of intermittent claudication and critical limb ischemia. Since the first case of CAD involving the external iliac artery was described by Atkins and Key in 1947, approximately 300 additional cases have been reported.

Objectives: The aim of this article is to report a rare vascular disorder, predominantly seen in young healthy men with minimal cardiovascular risk factors.

Methods: We report a rare case of cystic adventitial disease of a young policeman. To confirm the diagnosis, an ultrasonography and a conventional angiography were performed. The therapeutic approach was surgical first.

Results: The procedure was successful without any complication, and the patient was discharged to home 4 days after procedure.

Conclusion: While CAD is rare, the diagnosis should be suspected in a young patient who presents with arterial insufficiency and no risk factors for atherosclerosis. Catheter angiography is the investigation of choice in the absence of multislice CT and good MRA. It seems that the treatment that assures the best long-term results is reconstructive arterial bypass surgery.

Keywords: Adventitia; claudication; cyst; cystic adventitial disease; disease; peripheral vascular disease.

Publication types

  • Case Reports

MeSH terms

  • Adventitia / diagnostic imaging
  • Adventitia / surgery
  • Cysts* / complications
  • Cysts* / diagnostic imaging
  • Cysts* / surgery
  • Diagnosis, Differential
  • Humans
  • Intermittent Claudication / diagnostic imaging
  • Intermittent Claudication / etiology
  • Male
  • Peripheral Arterial Disease* / diagnostic imaging
  • Peripheral Arterial Disease* / etiology
  • Peripheral Arterial Disease* / surgery
  • Popliteal Artery / diagnostic imaging
  • Popliteal Artery / surgery