Deep Residual Separable Convolutional Neural Network for lung tumor segmentation

Abstract

Lung cancer is one of the deadliest types of cancers. Computed Tomography (CT) is a widely used technique to detect tumors present inside the lungs. Delineation of such tumors is particularly essential for analysis and treatment purposes. With the advancement in hardware technologies, Machine Learning and Deep Learning methods are outperforming the traditional methods in the field of medical imaging. In order to delineate lung cancer tumors, we have proposed a deep learning-based methodology which includes a maximum intensity projection based pre-processing method, two novel deep learning networks and an ensemble strategy. The two proposed networks named Deep Residual Separable Convolutional Neural Network 1 and 2 (DRS-CNN1 and DRS-CNN2) achieved better performance over the state-of-the-art U-net network and other segmentation networks. For fair comparison, we have evaluated the performances of all networks on Medical Segmentation Decathlon (MSD) and StructSeg 2019 datasets. The DRS-CNN2 achieved a mean Dice Similarity Coefficient (DSC) of 0.649, mean 95 Hausdorff Distance (HD95) of 18.26, mean Sensitivity 0.737 and a mean Precision of 0.765 on independent test sets.

Keywords: Atrous convolution; Deep learning; Lung cancer.