Application of a tungsten apron for occupational radiation exposure in nursing care of children with neuroblastoma during 131I-meta-iodo-benzyl-guanidine therapy

Sci Rep. 2022 Jan 7;12(1):47. doi: 10.1038/s41598-021-03843-2.

Abstract

The use of effective shielding materials against radiation is important among medical staff in nuclear medicine. Hence, the current study investigated the shielding effects of a commercially available tungsten apron using gamma ray measuring instruments. Further, the occupational radiation exposure of nurses during 131I-meta-iodo-benzyl-guanidine (131I-MIBG) therapy for children with high-risk neuroblastoma was evaluated. Attachable tungsten shields in commercial tungsten aprons were set on a surface-ray source with 131I, which emit gamma rays. The mean shielding rate value was 0.1 ± 0.006 for 131I. The shielding effects of tungsten and lead aprons were evaluated using a scintillation detector. The shielding effect rates of lead and tungsten aprons against 131I was 6.3% ± 0.3% and 42.1% ± 0.2% at 50 cm; 6.1% ± 0.5% and 43.3% ± 0.3% at 1 m; and 6.4% ± 0.9% and 42.6% ± 0.6% at 2 m, respectively. Next, we assessed the occupational radiation exposure during 131I-MIBG therapy (administration dose: 666 MBq/kg, median age: 4 years). The total occupational radiation exposure dose per patient care per 131I-MIBG therapy session among nurses was 0.12 ± 0.07 mSv. The average daily radiation exposure dose per patient care among nurses was 0.03 ± 0.03 mSv. Tungsten aprons had efficient shielding effects against gamma rays and would be beneficial to reduce radiation exposures per patient care per 131I-MIBG therapy session.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3-Iodobenzylguanidine / therapeutic use*
  • Child
  • Child, Preschool
  • Female
  • Gamma Rays
  • Humans
  • Infant
  • Iodine Radioisotopes
  • Male
  • Neuroblastoma / radiotherapy*
  • Nuclear Medicine / methods
  • Nurses
  • Occupational Exposure / prevention & control*
  • Occupational Injuries / nursing
  • Occupational Injuries / prevention & control
  • Protective Clothing
  • Radiation Exposure / prevention & control
  • Radiation Injuries / nursing*
  • Radiation Injuries / prevention & control*
  • Radiation Protection / methods*
  • Tungsten

Substances

  • Iodine Radioisotopes
  • Iodine-131
  • 3-Iodobenzylguanidine
  • Tungsten