Sweet targets: sugar nucleotide biosynthesis inhibitors

Future Med Chem. 2022 Mar;14(5):295-298. doi: 10.4155/fmc-2021-0286. Epub 2022 Jan 7.

Authors

Sanaz Ahmadipour¹, Jóhannes Reynisson^{2

3}, Robert A Field¹, Gavin J Miller^{4

3}

Affiliations

¹ Department of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
² Hornbeam Building, School of Pharmacy & Bioengineering, Keele University, Keele, Staffordshire, ST5 5BG, UK.
³ Centre for Glycoscience Research, Keele University, Keele, Staffordshire, ST5 5BG, UK.
⁴ Lennard-Jones Laboratory, School of Chemical & Physical Sciences, Keele University, Keele, Staffordshire, ST5 5BG, UK.

PMID: 34994583
DOI: 10.4155/fmc-2021-0286

No abstract available

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Aspergillus / enzymology
Bacterial Proteins / antagonists & inhibitors
Bacterial Proteins / metabolism
Carbohydrate Dehydrogenases / antagonists & inhibitors
Carbohydrate Dehydrogenases / metabolism
Enzyme Inhibitors / chemistry*
Enzyme Inhibitors / metabolism
Fungal Proteins / antagonists & inhibitors
Fungal Proteins / metabolism
Galactose / analogs & derivatives
Galactose / biosynthesis
Intramolecular Transferases / antagonists & inhibitors
Intramolecular Transferases / metabolism
Nucleoside Diphosphate Sugars / biosynthesis
Nucleotides / biosynthesis*
Nucleotidyltransferases / antagonists & inhibitors
Nucleotidyltransferases / metabolism
Pseudomonas aeruginosa / enzymology
Uridine Diphosphate / analogs & derivatives
Uridine Diphosphate / biosynthesis

Substances

Bacterial Proteins
Enzyme Inhibitors
Fungal Proteins
Nucleoside Diphosphate Sugars
Nucleotides
uridine diphosphate galactofuranose
GDP mannuronic acid
Uridine Diphosphate
Carbohydrate Dehydrogenases
GDPmannose dehydrogenase
Nucleotidyltransferases
UDPacetylglucosamine pyrophosphorylase
Intramolecular Transferases
UDP-galactopyranose mutase
Galactose