Resequencing of VEGFR3 pathway genes implicate GJC2 and FLT4 in the formation of primary congenital chylothorax

Am J Med Genet A. 2022 May;188(5):1607-1611. doi: 10.1002/ajmg.a.62643. Epub 2022 Jan 7.

Authors

Sophia Schneider^{1

2}, Ricarda Köllges^{1

2}, Jil D Stegmann^{1

2}, Frederic Thieme², Alina C Hilger^{1

2}, Lea Waffenschmidt², Julia Fazaal², Jeshurun C Kalanithy^{1

2}, Annegret Geipel³, Brigitte Strizek³, Kerstin U Ludwig², Heiko Reutter^{1

2

4}, Andreas Müller¹

Affiliations

¹ Department of Neonatology and Paediatric Intensive Care, University Hospital Bonn Center of Paediatrics, Bonn, Germany.
² Institute of Human Genetics, University Hospital Bonn, Bonn, Germany.
³ Department of Obstetrics and Prenatal Medicine, University Hospital Bonn, Bonn, Germany.
⁴ Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics and Adolescent Medicine, Friedrich-Alexander University Nürnberg-Erlangen, Erlangen, Germany.

PMID: 34994518
DOI: 10.1002/ajmg.a.62643

No abstract available

Publication types

Letter

MeSH terms

Chylothorax* / congenital
Chylothorax* / genetics
Connexins
Humans
Sequence Analysis, DNA
Vascular Endothelial Growth Factor Receptor-3 / genetics

Substances

Connexins
connexin 47
FLT4 protein, human
Vascular Endothelial Growth Factor Receptor-3

Supplementary concepts

Chylothorax, congenital