Carboxylato-Pillar[6]arene-Based Fluorescent Indicator Displacement Assays for Caffeine Sensing

Qunpeng Duan; Yibo Xing; Kainan Guo

doi:10.3389/fchem.2021.816069

Carboxylato-Pillar[6]arene-Based Fluorescent Indicator Displacement Assays for Caffeine Sensing

Front Chem. 2021 Dec 21:9:816069. doi: 10.3389/fchem.2021.816069. eCollection 2021.

Authors

Qunpeng Duan¹, Yibo Xing¹, Kainan Guo¹

Affiliation

¹ School of Chemical and Printing-dyeing Engineering, Henan University of Engineering, Zhengzhou, China.

Abstract

In the present work, we have developed a new indicator displacement system based on pillararene for anionic water-soluble carboxylato pillar [6] arene (WP6) and aromatic fluorescent dye safranine T (ST). A large fluorescence enhancement and colour change of ST were observed after complexation with electron-rich cavity in WP6 because of host-guest twisted intramolecular charge-transfer interactions. The constructed pillararene-indicator displacement system can be applied for caffeine selective detection in water.

Keywords: caffeine sensing; fluorescent; host-guest complex; indicator displacement assay; pillararene.