Longitudinal study of patients' health-related quality of life using EQ-5D-3L in 11 Swedish National Quality Registers

Fitsum Sebsibe Teni; Ola Rolfson; Nancy Devlin; David Parkin; Emma Nauclér; Kristina Burström; Swedish Quality Register (SWEQR) Study Group

doi:10.1136/bmjopen-2020-048176

Longitudinal study of patients' health-related quality of life using EQ-5D-3L in 11 Swedish National Quality Registers

BMJ Open. 2022 Jan 6;12(1):e048176. doi: 10.1136/bmjopen-2020-048176.

Authors

Fitsum Sebsibe Teni¹, Ola Rolfson^{2

3

4}, Nancy Devlin^{5

6}, David Parkin^{6

7}, Emma Nauclér⁴, Kristina Burström^{2

8

9}; Swedish Quality Register (SWEQR) Study Group

Collaborators

Swedish Quality Register (SWEQR) Study Group:
Allan Abbott, Magnus Ekström, Magnus Forssblad, Peter Fritzell, Åsa Jonsson, Mikael Landén, Michael Möller, Malin Regardt, Björn Rosengren, Marcus Schmitt-Egenolf, Johanna Vinblad, Annette W-Dahl

Affiliations

¹ Health Outcomes and Economic Evaluation Research Group, Stockholm Centre for Healthcare Ethics, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden fitsum.teni@ki.se.
² Health Outcomes and Economic Evaluation Research Group, Stockholm Centre for Healthcare Ethics, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden.
³ Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
⁴ Swedish Hip Arthroplasty Register, Gothenburg, Sweden.
⁵ Health Economics, The University of Melbourne School of Population and Global Health, Melbourne, Victoria, Australia.
⁶ Office of Health Economics, London, UK.
⁷ City University of London, London, UK.
⁸ Equity and Health Policy Research Group, Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
⁹ Health Care Services, Region Stockholm, Stockholm, Sweden.

Abstract

Objective: To compare problems reported in the five EQ-5D-3L dimensions and EQ VAS scores at baseline and at 1-year follow-up among different patient groups and specific diagnoses in 11 National Quality Registers (NQRs) and to compare these with the general population.

Design: Longitudinal, descriptive study.

Participants: 2 66 241 patients from 11 NQRs and 49 169 participants from the general population were included in the study.

Primary and secondary outcome measures: Proportions of problems reported in the five EQ-5D-3L dimensions, EQ VAS scores of participants' own health and proportions of participants and mean/median EQ VAS score in the Paretian Classification of Health Change (PCHC) categories.

Results: In most of the included registers, and the general population, problems with pain/discomfort were the most frequently reported at baseline and at 1-year follow-up. Mean EQ VAS score (SD) ranged from 45.2 (22.4) among disc hernia patients to 88.1 (15.3) in wrist and hand fracture patients at baseline. They ranged from 48.9 (20.9) in pulmonary fibrosis patients to 83.3 (17.4) in wrist and hand fracture patients at follow-up. The improved category of PCHC, improvement in at least one dimension without deterioration in any other, accounted for the highest proportion in several diagnoses, corresponding with highest improvement in mean EQ VAS score.

Conclusions: The study documented self-reported health of several different patient groups using the EQ-5D-3L in comparing with the general population. This demonstrated the important role of patient-reported outcomes in routine clinical care, to assess and follow-up health status and progress within different groups of patients. The EQ-5D-3L descriptive system and EQ VAS have an important role in providing a 'common denominator', allowing comparisons across NQRs and specific diagnoses.

Trial registration number: ClinicalTrials.gov (NCT04359628).

Keywords: health economics; internal medicine; orthopaedic & trauma surgery.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Health Status*
Humans
Longitudinal Studies
Quality of Life*
Surveys and Questionnaires
Sweden / epidemiology

Associated data

ClinicalTrials.gov/NCT04359628