Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus Hospitalizations: National Inpatient Sample, 2016-2019

Eili Y Klein; Xianming Zhu; Molly Petersen; Eshan U Patel; Sara E Cosgrove; Aaron A R Tobian

doi:10.1093/ofid/ofab585

Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus Hospitalizations: National Inpatient Sample, 2016-2019

Open Forum Infect Dis. 2021 Nov 22;9(1):ofab585. doi: 10.1093/ofid/ofab585. eCollection 2022 Jan.

Authors

Eili Y Klein^{1

2}, Xianming Zhu³, Molly Petersen³, Eshan U Patel^{3

4}, Sara E Cosgrove⁵, Aaron A R Tobian^{3

4

5}

Affiliations

¹ Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
² Center for Disease Dynamics, Economics & Policy, Washington DC, USA.
³ Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
⁴ Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
⁵ Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Abstract

Data from the National Inpatient Sample demonstrate that methicillin-resistant Staphylococcus aureus (MRSA)-related septicemia hospitalizations increased from 1.67 (95% CI, 1.63-1.72) to 1.94 (95% CI, 1.88-2.00; P _trend < .001) discharges per 1000 hospitalizations between 2016 and 2019. Regionally, the trends were similar. Rates of MSSA-related septicemia and pneumonia hospitalizations also increased significantly over this time period.

Keywords: MRSA; MSSA; NIS; National Inpatient Sample; antimicrobial stewardship; methicillin-resistant Staphylococcus aureus; methicillin-sensitive Staphylococcus aureus.

Abstract

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