Review of Immunohistochemistry Biomarkers in Pancreatic Cancer Diagnosis

Front Oncol. 2021 Dec 20:11:799025. doi: 10.3389/fonc.2021.799025. eCollection 2021.

Abstract

Pancreatic cancer is one of the cancer types with poor prognosis and high rate of mortality. Diagnostic modalities for early detection of pancreatic cancer have been among the academic concerns. On account of the potential role of immunohistochemistry (IHC) biomarkers in overcoming certain limitations of imaging diagnostic tools in discriminating pancreatic cancer tissues from benign ones, a growing scholarly attention has been given to the diagnostic efficacy of IHC biomarkers for pancreatic cancer. This review will analyze and synthesize published articles to provide an insight into potential IHC biomarkers for pancreatic cancer diagnosis.

Keywords: biomarker; immunohistochemistry; pancreatic cancer; sensitivity; specificity.

Publication types

  • Review