Skeletal changes are a common complication in patients with chronic kidney disease and traditionally labelled as renal osteodystrophy. Uremic leontiasis ossea is a rare and severe form of renal osteodystrophy with characteristic overgrowth of the craniofacial bones. Imaging, in particular computed tomography, is valuable for the diagnosis and management of such rare condition. Uremic leontiasis ossea has distinctive imaging features with significant overgrowth of the jaw and characteristic internal serpiginous tunneling. The recognition of its radiological appearance and abrupt management are essential to avoid its devastating esthetic and functional impairments.
Keywords: 3D, three-dimensional; 4D, four-dimensional; CKD, chronic kidney disease; CKD-MBD, chronic kidney disease–mineral and bone disorder; CT, Computed tomography; Computed tomography; Craniofacial; ESRD, end-stage renal disease; KDIGO, Kidney Disease-Improving Global Outcomes; Leontiasis ossea; MRI, Magnetic resonance imaging; PTH, parathyroid hormone; ROD, renal osteodystrophy; Renal osteodystrophy; SHPT, secondary hyperparathyroidism; ULO, uremic leontiasis ossea; Uremic.
© 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington.