Pulmonary blastoma in a pregnant woman: a case report and brief review of the literature

BMC Pulm Med. 2022 Jan 4;22(1):8. doi: 10.1186/s12890-021-01804-z.

Abstract

Background: Pulmonary blastoma (PB) comprises a rare heterogeneous group of lung tumours typically containing immature epithelial and mesenchymal structures that imitate the embryonic lung tissue and extremely rarely occurs during pregnancy. Although cough and haemoptysis are the most common PB symptoms, they usually indicate other serious pregnancy-related complications.

Case presentation: The article presents the unusual case of a 22-year-old pregnant woman diagnosed with PB during pregnancy.

Conclusions: PB is characterized by poor prognosis and patients' outcome relies on a rapid diagnosis. Surgery remains the most common and effective treatment. Due to the extreme rarity, the literature contains only single mentions of PB in pregnancy, thus its impact on the course of pregnancy and the developing fetus remains unknown.

Keywords: Case report; Haemoptysis; Histopathology; Lung cancer; Pregnancy; Pulmonary blastoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cesarean Section
  • Chemotherapy, Adjuvant / methods
  • Female
  • Humans
  • Infant, Newborn
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / pathology
  • Lung Neoplasms / surgery
  • Male
  • Pregnancy
  • Pulmonary Blastoma / diagnosis*
  • Pulmonary Blastoma / drug therapy
  • Pulmonary Blastoma / pathology
  • Pulmonary Blastoma / surgery
  • Treatment Outcome
  • Young Adult