Association between long-term exposure to ambient particulate matter and blood pressure, hypertension: an updated systematic review and meta-analysis

Int J Environ Health Res. 2023 Mar;33(3):268-283. doi: 10.1080/09603123.2021.2022106. Epub 2022 Jan 4.

Abstract

Evidence of more recent studies should be updated to evaluate the effect of long-term exposure to particulate matter (PM) on blood pressure and hypertension. Studies of long-term effects of PM1, PM2.5 and PM10 on blood pressure (SBP, DBP, MAP), hypertension were searched in Pubmed, Web of Science and Embase before May, 2021. Meta-analysis of 41 studies showed that exposure to PM1, PM2.5 was associated with SBP (1.76 mmHg (95%CI:0.71, 2.80) and 0.63 mmHg (95%CI:0.40, 0.85), per 10 μg/m3 increase in PM), all three air pollutants (PM1, PM2.5, PM10) was associated with DBP (1.16 mmHg (95%CI:0.34, 1.99), 0.31 mmHg (95%CI:0.16, 0.47), 1.17 mmHg (95%CI:0.24, 2.09), respectively. As for hypertension, PM1, PM2.5 and PM10 were all significantly associated with higher risk of hypertension (OR=1.27 (95%CI:1.06, 1.52), 1.15 (95%CI:1.10, 1.20) and 1.11 (95%CI:1.07, 1.16). In conclusion, our study indicated a positive association between long-term exposure to particulate matter and increased blood pressure, hypertension.

Keywords: Air pollution; Blood pressure; Hypertension; Meta-analysis; Particulate matter.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Air Pollutants* / analysis
  • Air Pollutants* / toxicity
  • Air Pollution* / adverse effects
  • Air Pollution* / analysis
  • Blood Pressure
  • China
  • Environmental Exposure / adverse effects
  • Environmental Exposure / analysis
  • Humans
  • Hypertension* / chemically induced
  • Hypertension* / epidemiology
  • Particulate Matter / analysis
  • Particulate Matter / toxicity

Substances

  • Particulate Matter
  • Air Pollutants